| CatalogCode: | NB100-56680 |
| ProductName: | Punctin Antibody |
| Product Description: | Mouse Monoclonal anti-Punctin (30D445.1) |
| Clone: | 30D445.1 |
| Clonality: | Monoclonal |
| Immunogen: | This monoclonal antibody was raised against a synthetic peptide containing amino acid residues 226-240 (YLETKTLQGTKGENS) of human punctin, GenBank no. gi 21327691 ref NP_443098.2 The immunogen sequence is 100% conserved in rat and mouse. |
| Specificity: | In human muscle, a 60 kDa band is observed. Punctin may be expressed as various isoforms with varying molecular wieght. The punctin antibody recognizes isoforms which contain the sequence used for immunogen ((YLETKTLQGTKGENS). |
| CrossReactivity: | Human, Mouse, Rat Not yet tested in other species. |
| Packaging: | 0.2 ml of Mouse Ascites |
| Uses: | WB: 1:250-1:500~; IHC: test |
| Background: | Punctin (ADAMTSL-1) is a secreted molecule, expressed in adult skeletal muscle, resembling members of the ADAMTS family of proteases, containing four thrombospondin type I repeats. Human punctin cleaves aggrecan and is thereby classified as an aggrecanase. Like the ADAMTS proteases, each domain in punctin has an even number of cysteine residues suggesting that each domain may have internal disulfide bonds and that punctin consists of a series of independently folded and disulfide-bonded domains. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Ascites |
| Isotype: | IgM, k |
| Host_Name: | Mouse |
| Buffer: | PBS containing 0.02% sodium azide. Sodium azide is highly toxic. |
| ListPrice: | 295 |
| AppSummary: | IHC, WB |
| SpeciesSummary: | Hu, Mu, Rt |
| ProteinTarget: | Punctin |
| PackageSize: | 0.2 ml |