| CatalogCode: | NB100-56498 |
| ProductName: | SSTR5 Antibody |
| Product Description: | Rabbit Polyclonal anti-SSTR5 |
| Clonality: | Polyclonal |
| Immunogen: | A portion of amino acids 300-350 of human SSTR5 was used as the immunogen. |
| Specificity: | The amino acid sequence used as immunogen is 100% homologous in human and 94% in chimp. The expected size of SSRT5, based on amino acid content, is approximately 40 kD. It is believed that the 5-10 kD increase in observed size is due to glycosylation. |
| CrossReactivity: | Human Not yet tested in other species. |
| Packaging: | 0.1 mg of Rabbit Peptide Affinity Purified |
| Uses: | WB: 0.1-1 ug/ml |
| Background: | Principal Names: Somatostatin receptor 5 (SSTR5); SS5R; Official Gene Symbol: SSTR5 Gen Bank Accession Number: NP_001044 Gene ID: 6755 (human) Gene Map Locus: 16p13.3 (human) Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Peptide Affinity Purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic. |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Somatostatin receptor 5 antibody |
| ProteinTarget: | SSTR5 |
| PackageSize: | 0.1 mg |
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