| CatalogCode: | NB100-56454 |
| ProductName: | Smallpox B5R Antibody |
| Product Description: | Rabbit Polyclonal anti-Smallpox B5R |
| Clonality: | Polyclonal |
| Immunogen: | Amino acids 180-194 (HYKKSESESYNELIK) of the B5R protein were used as the immunogen. |
| Specificity: | The amino acid sequence used as immunogen is 100% homologous in human, camel, rabbit and cow, and 93% in monkey. |
| CrossReactivity: | Camel, Cow, Human, Rabbit Not yet tested in other species. |
| Packaging: | 0.1 mg of Rabbit Affinity Purified |
| Uses: | WB: 0.1-1 ug/ml |
| Background: | Vaccinia virus, a member of Poxviridae family, is a dsDNA enveloped virus. It consists of 4 types of virion stages among which extracellular enveloped virus (EEV) is critical for cell-to-cell and long range viral infection. B5R is an EEV-specific Type I membrane glycoprotein essential for EEV formation. It consists of a large ectodomain containing regions similar to SCR domains of complement regulatory proteins followed by a transmembrane region and a cytoplasmic tail. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, incorporation of the protein into EEV and for EEV formation. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Affinity Purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic. |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Bo, Hu, Rb |
| ProteinTarget: | Smallpox B5R |
| PackageSize: | 0.1 mg |
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