| CatalogCode: | NB100-56407 |
| ProductName: | IL-24 Antibody |
| Product Description: | Rabbit Polyclonal anti-IL-24 |
| Clonality: | Polyclonal |
| Immunogen: | A portion of amino acids 100-150 of human IL-24 were used as the immunogen. |
| CrossReactivity: | Human Not yet tested in other species. |
| Packaging: | 0.1 mg of Rabbit Affinity Purified |
| Uses: | WB: 0.5-3 ug/ml~; Flow: 2-5 ug/10; 6 cells |
| Control: | Jurkat |
| Background: | Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Affinity Purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic. |
| ListPrice: | 295 |
| AppSummary: | WB, FACS |
| SpeciesSummary: | Hu |
| ALTnames: | anti-MDA-7 antibody |
| ProteinTarget: | IL-24 |
| PackageSize: | 0.1 mg |
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