| CatalogCode: | NB100-56047 |
| ProductName: | SARS-Spike protein Antibody |
| Product Description: | Rabbit Polyclonal anti-SARS-Spike protein |
| Clonality: | Polyclonal |
| Immunogen: | The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 19-35 of the putative SARS Spike glycoprotein (Genbank accession no. NP_828851). |
| Specificity: | The antibody was tested on a cell line transfected with a partial-length cDNA coding for the N-terminal portion of SARS Spike protein with a predicted molecular weight of 68 kDa. |
| CrossReactivity: | Human Not yet tested in other species. |
| Packaging: | 0.1 mg of Rabbit Affinity Purified |
| Uses: | WB: 0.5-2 ug/ml ~; ELISA: 0.5-2 ug/ml |
| Control: | transfected mouse melanoma cell lysate |
| Background: | It has recently been shown that SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS patients. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Affinity Purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic. |
| ListPrice: | 295 |
| AppSummary: | WB, ELISA |
| SpeciesSummary: | Hu |
| ProteinTarget: | SARS-Spike protein |
| PackageSize: | 0.1 mg |