| CatalogCode: | NB100-55942 |
| ProductName: | Bcl-2 (NT) Antibody |
| Product Description: | Rabbit Polyclonal anti-Bcl-2 (NT) |
| Clonality: | Polyclonal |
| Immunogen: | Human Bcl-2 (NT) peptide. |
| CrossReactivity: | Human, Mouse Not yet tested in other species. |
| Packaging: | 0.1 mg of Rabbit Affinity Purified |
| Uses: | WB: 1-2 ug/ml ~; IHC (paraffin): 2 ug/ml |
| Control: | Daudi cell lysates. |
| Background: | Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-2 is the founding member of a family of over 20 proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-2 is an inner mitochondrial membrane protein that inhibits apoptosis. It is thought to act by interacting with pro-apoptotic Bcl-2 family members such as Bak and Bad. Overexpression of Bcl-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity Purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | PBS containing 0.02% sodium azide. |
| ListPrice: | 295 |
| AppSummary: | IHC, WB |
| SpeciesSummary: | Hu, Mu |
| ProteinTarget: | Bcl-2 (NT) |
| PackageSize: | 0.1 mg |