| CatalogCode: | NB100-55409 |
| ProductName: | PRPF31 Antibody |
| Product Description: | Goat Polyclonal anti-PRPF31 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, KELGNSLDKCKNNEN, representing the internal region of the human protein according to NP_056444.2 |
| Epitope: | KELGNSLDKCKNNEN |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Approx 60kDa band observed in lysates of cell lines A431 and HeLa (calculated MW of 55.4kDa according to NP_056444.2). Recommended concentration: 1-3ug/ml.An additional band of unknown identity was also consistently observed at 35kDa. This band was successfully blocked by incubation with the immunising peptide. Also a band of 28kDa was consistently observed, however this band was not blocked by the immunizing peptide and it is therefore a non-specific signal. We call for caution when used for other assays than Western blot. |
| Background: | Retinitis pigmentosa (RP) is a clinically and genetically heterogeneous group of retinal dystrophies characterized by a progressive degeneration of photoreceptors, eventually resulting in severe visual impairment. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-PRPF31 antibody, anti-PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) antibody, anti-DKFZp566J153 antibody, anti-NY-BR-99 antibody, anti-PRP31 antibody, anti-RP11antibody, anti-PRP31 pre-mRNA processing factor 31 homolog (yeast) antibody, anti-pre-mRNA processing factor 31 homolog antibody, anti-pre-mRNA processing factor 31 homolog (yeast)antibody, anti- antibody |
| ProteinTarget: | PRPF31 |
| PackageSize: | 0.1 mg |
| Homology: | Human, Mouse, Rat, Dog |
| GeneralRef: | Yuan L, Kawada M, Havlioglu N, Tang H, Wu JY. Mutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells. J Neurosci. 2005 Jan 19;25(3):748-57. PMID: 15659613 |
| NotesMain: | Other Gene IDs: 68988 (mouse); |
| Gene_Id: | 26121 |
| Omim_ID: | H00026121-A01 |
order or
more information: | company product webpage |
| request information: |
|