| CatalogCode: | NB100-55399 |
| ProductName: | GATA5 Antibody |
| Product Description: | Goat Polyclonal anti-GATA5 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, C-ELAARPGWAQTATAD, representing the internal region of the human protein according to NP_536721.1 |
| Epitope: | ELAARPGWAQTATAD |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 40kDa band observed in lysates of liver cell line HepG2 (calculated MW of 41.3kDa according to NP_536721.1). Recommended concentration: 0.3-1ug/ml. |
| Control: | HepG2 cell lysate |
| Background: | The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-GATA5 antibody, anti-GATA binding protein 5antibody, anti-bB379O24.1antibody, anti-GATA binding factor-5 antibody, anti-GATA-binding protein 5 antibody, anti-transcription factor GATA-5antibody, anti- antibody |
| ProteinTarget: | GATA5 |
| PackageSize: | 0.1 mg |
| Homology: | Human |
| GeneralRef: | Belinsky SA, Liechty KC, Gentry FD, Wolf HJ, Rogers J, Vu K, Haney J, Kennedy TC, Hirsch FR, Miller Y, Franklin WA, Herman JG, Baylin SB, Bunn PA, Byers T. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Res. 2006 Mar 15;66(6):3338-44. PMID: 16540689 |
| Gene_Id: | 140628 |
| Omim_ID: | H00002627-A01 |
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