| CatalogCode: | NB100-55398 |
| ProductName: | EPHB2 Antibody |
| Product Description: | Goat Polyclonal anti-EPHB2 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, C-QKDRNHRPKFGQ, representing the internal region of the human protein according to NP_004433.2; NP_059145.2 |
| Epitope: | QKDRNHRPKFGQ |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:4,000. Approx 60kDa band observed in Human Lung and Placenta lysates (calculated MW of 110kDa according to NP_059145.2 and NP_004433.2). The observed molecular weight corresponds to earlier findings in literature (Litterst et al, J Biol Chem. 2007 Apr 10; PMID: 17428795). Recommended concentration: 1-3ug/ml. |
| Background: | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-EPHB2antibody, anti-EPH receptor B2antibody, anti-DRT antibody, anti-EPHT3 antibody, anti-ERK antibody, anti-Hek5 antibody, anti-MGC87492 antibody, anti-Tyro5antibody, anti-developmentally-regulated eph-related tyrosine kinase antibody, anti-elk-related tyrosine kinase antibody, anti-eph tyrosine kinase 3 antibody, anti-ephrin receptor EphB2antibody, anti- antibody |
| ProteinTarget: | EPHB2 |
| PackageSize: | 0.1 mg |
| Homology: | Human, Mouse, Rat, Dog |
| GeneralRef: | Cramer KS, Cerretti DP, Siddiqui SA. EphB2 regulates axonal growth at the midline in the developing auditory brainstem. Dev Biol. 2006 Apr 13; [Epub ahead of print] PMID: 16626680 |
| NotesMain: | Other Gene IDs: 13844 (mouse); |
| Gene_Id: | 2048 |
| Omim_ID: | H00002048-A01 |
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