| CatalogCode: | NB100-552 |
| ProductName: | WAPL Antibody |
| Product Description: | Rabbit Polyclonal anti-WAPL |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide which maps to a region between residues 1125 and 1175 of human wings apart like/KIAA0261 using the numbering given in TrEMBL entry Q7Z5K2 (GeneID 23063). |
| Specificity: | NB 100-552 is specific for human WAPL protein. |
| CrossReactivity: | Human. Other species not tested. Reactivity with mouse WAPL is expected owing to complete identity between this ortholog and human WAPL at the site to which the epitope maps. |
| Packaging: | 0.1 ml protein G purified Rabbit antisera. |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested starting dilutions are as follows. Western Blot: 1:2,500 - 1:10,000 Immunoprecipitation: not tested Histo/Cytochemistry: not tested*In some cases, the antibody may be diluted further than indicated. |
| Background: | The hWAPL mRNA was predominantly expressed in uterine cervical cancer, with weak expression in all other normal and tumor tissues examined. hWAPL expression in benign epithelia was confined to the basal cell layers, whereas in dysplasias it increasingly appeared in more superficial cell layers and showed a significant correlation with severity of dysplasia. Diffuse hWAPL expression was found in all invasive squamous cell carcinomas examined. These results demonstrate that hWAPL is associated with cell growth, and the hWAPL expression may play a significant role in cervical carcinogenesis and tumor progression. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | protein G purified |
| Host_Name: | Rabbit |
| Buffer: | PBS, pH 7.2 |
| ListPrice: | 285 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-WAPL antibody, anti-hWAPL antibody, anti-human homolog of wings apart like protein antibody, anti-FOE friend of EBNA2 antibody, anti-KIAA0261 antibody |
| ProteinTarget: | WAPL antibody |
| PackageSize: | 0.1 ml |
| NotesMain: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |
| Gene_Id: | 23063 |
| Omim_ID: | NB100-62983 |