| Catalog Code: | NB100-540 |
| Product Type: | Primary Antibody |
| Product Name: | XRCC1 Antibody |
| List Price: | 330 |
| Clonality: | Polyclonal |
| Gene ID: | 7515 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-XRCC-1 [Ser475] |
| Phosphorylated: | Ser475 |
| Cross Reactivity: | Human. Other species have not been tested. |
| Species Summary: | Hu |
| Background: | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase t |
| Alternate Names: | anti-XRCC1 antibody, anti-X-ray Repair Complementing protein 1 antibody |
| Immunogen: | Antibody was affinity purified using an epitope specific to phosphorylation at Ser 475 of XRCC1 using the numbering given in SwissProt entry P18887 (GeneID 7515). |
| Specificity: | NB 100-540 is specific for human phospho-XRCC1 protein. |
| Packaging: | 0.1 ml of affinity purified rabbit sera in a Tris-citrate/phosphate (pH 7-8) buffer with 0.1% sodium azide. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested starting dilutions are as follows. Western Blot: 1:1,000 - 1:5,000 Immunoprecipitation: not tested Histo/Cyto |
| Application Summary: | WB |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |