| CatalogCode: | NB100-53809 |
| ProductName: | GFAP Antibody |
| Product Description: | Goat Polyclonal anti-GFAP |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, C-DGEVIKESKQEHKD, representing the C Terminus of the human protein according to NP_002046.1 |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 48kDa band observed in Mouse Brain lysates (calculated MW of 49.8kDa according to mouse NP_034407.2 and human NP_002046.1). Recommended concentration: 1-3ug/ml. |
| Control: | Mouse Brain lysate |
| Background: | Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily and specifically expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. In addition neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Mu |
| ALTnames: | anti-GFAP antibody, anti-glial fibrillary acidic protein antibody, anti-FLJ45472 antibody, anti-intermediate filament protein antibody |
| ProteinTarget: | GFAP |
| PackageSize: | 0.1 mg |
| Homology: | Human, Mouse, Rat, Dog |
| GeneralRef: | Korolainen MA, Auriola S, Nyman TA, Alafuzoff I, Pirttila T. Proteomic analysis of glial fibrillary acidic protein in Alzheimer's disease and aging brain.Neurobiol Dis. 2005 Dec;20(3):858-70. Epub 2005 Jun 27. PMID: 15979880 |
| Gene_Id: | 2670 |
| Gene_Symbol: | GFAP |
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