| Catalog Code: | NB100-53794 |
| Product Type: | Primary Antibody |
| Product Name: | ZMPSTE24 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 10269 |
| Host: | Goat |
| Isotype: | IgG |
| Product Description: | Goat Polyclonal anti-ZMPSTE24 |
| Cross Reactivity: | Human. Other species not tested. |
| Species Summary: | Hu |
| Background: | ZMPSTE24 is a zinc metalloprotease involved in the post-translational processing of LMNA precursors. Mutations in ZMPSTE24 have been associated with human diseases, often due to the accumulation of LMNA precursors. It is possible that ZMPSTE24, due to its |
| Alternate Names: | anti-ZMPSTE24 antibody, anti-zinc metallopeptidase (STE24 homolog antibody, anti-yeast) antibody, anti-FACE-1 antibody, anti-FACE1 antibody, anti-FLJ14968 antibody, anti-MADB antibody, anti-STE24 antibody, anti-Ste24p antibody, anti-CAAX prenyl protease a |
| Immunogen: | Synthetic peptide, C-ERLQALKTMKQH, representing the C Terminus of the human protein according to NP_005848.2 |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Approx 55kDa band observed in Human Skin lysates (calculated MW of 54.8kDa according to NP_005848.2). Recommended concentration: 0.5-1.5ug/ml. |
| Application Summary: | ELISA, WB |
| General References: | Fong LG, Frost D, Meta M, Qiao X, Yang SH, Coffinier C, Young SG. A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.Science. 2006 Mar 17;311(5767):1621-3. Epub 2006 Feb 16. PMID: 16484451 |
| Gene Symbol: | ZMPSTE24 |