| CatalogCode: | | NB100-501SS |
| ProductName: | | PP2A Antibody |
| Product Description: | | Mouse Monoclonal anti-PP2A (TQ11-1G6) - Sample Size |
| Clone: | | TQ11-1G6 |
| Clonality: | | Monoclonal |
| Immunogen: | | Human PP2A B56 gamma 3 (PPP2R5C transcript variant 1). |
| Epitope: | | C-terminus |
| Specificity: | | This antibody is specific for PP2A (B56 gamma 3 subunit) protein. This antibody does not recognize the B56 gamma 1 isoform of PP2A. |
| CrossReactivity: | | Human and mouse. Other species have not been tested. |
| Packaging: | | 0.025 ml protein G purified Mouse ascites. |
| Uses: | | By Western blot, this antibody recognizes overexpressed hPP2A B56gamma3 protein in transfected cells. Bands at ~50 and 35 kDa may also be seen. Western Blot analysis of endogenous samples is not recommended due to high background. Has been shown to work effectively for immunoprecipitation, see Lin et al. Suggested working dilutions: * Western Blot - 1:1,000 (on transfected cell lysates). Immunoprecipitation - See Lin et al |
| Background: | | Phosphatases are involved in the regulation of MAP kinases. Protein phosphatase 2A (PP2A) is a critical component of the pathway responsible for p38 MAPK up-regulation of SERT catalytic activity. |
| ProductRef: | | 1. Lin, S. S., Bassik, M. C., Suh, H., Nishino, M., Arroyo, J. D., Hahn, W. C., Korsmeyer, S. J., and Roberts, T. M. (2006) PP2A Regulates BCL-2 Phosphorylation and Proteasome-mediated Degradation at the Endoplasmic Reticulum, 281, 23003-23012. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | protein G purified |
| Isotype: | | IgG1 kappa |
| Host_Name: | | Mouse |
| ListPrice: | | 100 |
| NovusRef: | | 1. Lin, S., et al. PP2A Regulates BCL-2 Phosphorylation and Proteasome-mediated Degradation at the Endoplasmic Reticulum J. Biol. Chem., Aug 2006; 281: 23003-23012. 2. Kumamoto, C.A. A contact-activated kinase signals candida albicans invasive growth and biofilm development. PNAS. 102:5576-5581, 2005. |
| AppSummary: | | WB, IP |
| SpeciesSummary: | | Hu, Mu |
| ALTnames: | | anti-PP2A antibody, anti-Protein Phosphatase 2A antibody, anti-PP2CB antibody, anti-PPP2CB antibody, anti-Protein Phosphatase 2 antibody, anti-Catalytic Subunit Beta Isoform antibody, anti-Serine/threonine-protein phosphatase 2A antibody, anti-PPP2R5C antibody, anti-B' alpha regulatory subunit antibody, anti-B56G antibody, anti-IMYPNO1 antibody, anti-KIAA0044 antibody, anti-MGC23064 antibody, anti-PP2A B subunit B' gamma isoform antibody, anti-PP2A B subunit B56 gamma isoform antibody, anti-PP2A B subunit PR61 gamma isoform antibody, anti-PP2A B subunit R5 gamma isoform antibody, anti-PP2A subunit B B gamma isoform antibody, anti-PP2A subunit B B55 gamma isoform antibody, anti-PP2A subunit B PR55 gamma isoform antibody, anti-PP2A subunit B R2 gamma isoform antibody, anti-PR61G antibody, anti-Protein phosphatase 2 regulatory subunit B (B56) gamma isoform antibody, anti-Renal carcinoma antigen NY REN 29 antibody, anti-Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform antibody, anti-Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antibody |
| PackageSize: | | 0.025 ml |
| Marker: | | Sample Size |
| NotesMain: | | This antibody recognizes the C-terminus of the protein. |
| more information: | | company product webpage |
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