| CatalogCode: | NB100-476 |
| ProductName: | DNA Polymerase delta Antibody |
| Product Description: | Mouse Monoclonal anti-DNA Polymerase delta (607) |
| Clone: | 607 |
| Clonality: | Monoclonal |
| Immunogen: | Recombinant protein, corresponding to amino acids 1-140 of the large subunit of Human DNA Polymerase delta. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | WB: Use at a dilution of 1/1000. Detects a band of approximately 130 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear |
| Background: | DNA polymerase d (delta) functions in DNA replication and DNA repair. It also possesses 3' to 5' exonuclease activity. In leading strand synthesis it requires the processivity factor, PCNA. It is also possibly involved in the completion of DNA synthesis during Okazaki fragment elongation following the initiation of synthesis by the DNA polymerase a/primase complex |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG |
| Host_Name: | Mouse |
| Buffer: | PBS |
| ListPrice: | 285 |
| NovusRef: | Kundu, C., et al. Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: implication of base excision repair pathways. Carcinogenesis.October 2007;28: 2089-2095. |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ProteinTarget: | DNA Polymerase delta antibody |
| PackageSize: | 0.1 mg |
| GeneralRef: | Liu L et al. Identification of a fourth subunit of mammalian DNA polymerase delta. J Biol Chem 275:18739-44 (2000). Jansson ZO & Habscher U Proliferating cell nuclear antigen: more than a clamp for DNA polymerases. Bioessays 19:967-75 (1997). |
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