| Catalog Code: | NB100-471 |
| Product Type: | Primary Antibody |
| Product Name: | WRN Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 7486 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-WRN |
| Cross Reactivity: | NB 100-471 reacts with human protein. Other species have not been tested. Reactivity with mouse WRN is unlikely owing to divergence between the mouse sequence and the peptide used for this antibody production. |
| Species Summary: | Hu |
| Background: | This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein |
| Alternate Names: | anti-HGNC 12791 antibody, anti-RECQ3 antibody, anti-RECQL2 antibody, anti-RECQL3 antibody, anti-werner syndrome helicase antibody, anti-werner syndrome protein antibody, anti-WRN antibody |
| Immunogen: | The epitope recognized by NB 100-471 maps to a region between residues 400-450 of human Werner Syndrome Helicase using the SwissProt entry Q14191 (GeneID 7486). |
| Specificity: | This antibody is specific for human WRN. |
| Packaging: | 0.1 ml of affinity purified rabbit sera in a Tris-citrate/phosphate (pH 7-8) buffer with 0.1% sodium azide. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | NB 100-471 may be used for Western Blot and immunoprecipitation. Suggested working dilutions: * Western Blot - 1:5,000-1:25,000 (ECL) Immunocytochemistry - Not Determined Immunoprecipitation - 2-5 ug/mg lysate*The investigator should determine the optimal |
| Application Summary: | WB, IP |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |