| Catalog Code: | NB100-456 |
| Product Type: | Primary Antibody |
| Product Name: | PCNA Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 5111 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-PCNA |
| Cross Reactivity: | NB 100-456 reacts with human protein. Other species have not been tested. Reactivity with mouse and Xenopus PCNA is likely owing to conservation between the mouse sequence and the peptide used for this antibody production. |
| Species Summary: | Hu |
| Background: | PCNA is a homotrimeric protein that is involved in DNA replication and DNA repair. It serves as a processivity factor for DNA polymerase delta. It has also been shown to interact with several other proteins that are involved in DNA replication and repair, |
| Alternate Names: | anti-Cyclin antibody, anti-DNA polymerase delta auxiliary protein antibody, anti-HGCN8729 antibody, anti-MGC8367 antibody, anti-polymerase delta accessory protein antibody, anti-Proliferating Cell Nuclear Antigen antibody |
| Immunogen: | The epitope recognized by NB 100-456 maps to a region between residues 75-125 of human proliferating cell nuclear antigen using the SwissProt entry P12004 (GeneID 5111). |
| Specificity: | This antibody is specific for human PCNA. |
| Packaging: | 0.1 ml of affinity purified rabbit sera in a Tris-citrate/phosphate (pH 7-8) buffer with 0.1% sodium azide. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | NB 100-456 may be used for Western Blot and immunoprecipitation. Suggested working dilutions: * Western Blot - 1:2,000-1:10,000 (ECL) Immunocytochemistry - Not Determined Immunoprecipitation - 2-5 ug/mg lysate*The investigator should determine the optimal |
| Application Summary: | WB, IP |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |