| CatalogCode: | | NB100-41432 |
| ProductName: | | UBCH7 Antibody |
| Product Description: | | Rabbit Polyclonal anti-UBCH7 |
| Clonality: | | Polyclonal |
| Immunogen: | | A synthetic peptide mapping to a region between residues 100 and the C-terminus (residue 154) of human Ubiquitin-Conjugating Enzyme H7 using the numbering given in entry NP_003338.1 (GeneID 7332). |
| CrossReactivity: | | Human. Other species not tested. |
| Packaging: | | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | | Immunohistochemistry - 1:100 - 1:500 |
| Background: | | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. UBCH7 catalyzes the covalent attachment of ubiquitin to other proteins and mediates the selective degradation of short-lived and abnormal proteins as well as playing a role in the E6/E6-AP-induced ubiquitination of p53/TP53. Expression of this protein is ubiquitous, with highest expression in testis. |
| Storage: | | Store at 4C. Do not freeze. |
| Purity: | | Immunogen affinity purified |
| Host_Name: | | Rabbit |
| Buffer: | | Tris-buffered Saline and 0.1% BSA |
| ListPrice: | | 350 |
| AppSummary: | | IHC |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-UBCH7 antibody, anti-Ubiquitin-Conjugating Enzyme H7 antibody, anti-UBE2L3 antibody, anti-Ubiquitin-Conjugating Enzyme E2L 3 antibody, anti-UbcM4 antibody, anti-L-UBC antibody, anti-E2-F1 antibody |
| ProteinTarget: | | UBCH7 |
| PackageSize: | | 0.1 ml |
| Gene_Id: | | 7332 |
| Omim_ID: | | NB100-2265 |
| more information: | | company product webpage |