| CatalogCode: | NB100-41400 |
| ProductName: | VDAC2 Antibody |
| Product Description: | Goat Polyclonal anti-VDAC2 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, CDSAKSKLTRNN, representing the internal region of the human protein according to NP_003366.2 |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx 32kDa band observed in Human Heart lysates (calculated MW of 31.6 kDa according to NP_003366.2). Recommended concentration: 0.3-1µg/ml. |
| Control: | Human Heart lysate |
| Background: | VDAC2 forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. VDAC2 interacts with hexokinases. It is present in the outer mitochondrial membrane. There are 4 isoforms as result of alternative splicing. It consists mainly of membrane spanning sided beta sheets, and belongs to the eukaryotic mitochondrial porin family. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-hVDAC2 antibody, anti-Outer mitochondrial membrane protein porin 2 antibody, anti-Voltage dependent anion selective channel protein 2 antibody |
| ProteinTarget: | VDAC2 (Internal) |
| PackageSize: | 0.1 mg |
| Homology: | Human, Mouse, Rat, Dog |
| GeneralRef: | Chandra D, Choy G, Daniel PT, Tang DG. Bax-dependent regulation of Bak by voltage-dependent anion channel 2. J Biol Chem. 2005 May 13;280(19):19051-61. Epub 2005 Mar 9. PMID: 15757910 |
| NotesMain: | GeneID: 7417;22334 (mouse); |
| Gene_Id: | 7417 |
| Omim_ID: | NB300-871 |