| CatalogCode: | NB100-41394 |
| ProductName: | STAT3 Antibody |
| Product Description: | Goat Polyclonal anti-STAT3 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, CRPESQEHPEADP, representing the internal region of the human protein according to NP_644805.1; NP_003141.2; NP_998827.1 |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 75kDa band observed in Human Heart and Human Liver lysates (calculated MW of 83.1kDa according to NP_998827.1). Recommended concentration: 1-3ug/ml. |
| Control: | Human Liver lysate |
| Background: | The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-STAT3 antibody, anti-signal transducer and activator of transcription 3 (acute-phase response factor) antibody, anti-APRF antibody, anti-FLJ20882 antibody, anti-MGC16063 antibody, anti-DNA-binding protein APRF antibody, anti-acute-phase response factor antibody, anti-signal transducer and activator of transcription 3 antibody |
| ProteinTarget: | STAT3 |
| PackageSize: | 0.1 mg |
| Homology: | Human, Mouse, Rat, Dog |
| GeneralRef: | Palmqvist L, Glover CH, Hsu L, Lu M, Bossen B, Piret JM, Humphries RK, Helgason CD. Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency. Stem Cells. 2005 May;23(5):663-80. PMID: 15849174 |
| NotesMain: | GeneID: 6774;20848 (mouse); 25125 (rat); This antibody is expected to recognise all three reported isoforms (NP_644805.1, NP_003141.2 and NP_998827.1). |
| Gene_Id: | 6774 |
| Omim_ID: | H00006774-M02 |