| CatalogCode: | NB100-41108 |
| ProductName: | LIPF Antibody |
| Product Description: | Goat Polyclonal anti-LIPF |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, NDIVSMISEDKK, representing the C Terminus of the human protein according to NP_004181.1 |
| CrossReactivity: | Expected based upon sequence homology: Human |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Preliminary experiments gave an approx 25kDa band in Human Duodenum lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 45.2kDa according to NP_004181.1. The25kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported? |
| Background: | Gene ID: 8513 **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| ListPrice: | 195 |
| SpeciesSummary: | Hu |
| ALTnames: | anti-LIPF antibody, anti-lipase antibody, anti-gastric antibody, anti-GL antibody, anti-HGL antibody, anti-HLAL antibody, anti-MGC138477 antibody, anti-MGC142271 antibody, anti-gastric lipase antibody, anti-gastric triacylglycerol lipase antibody |
| ProteinTarget: | LIPF |
| PackageSize: | 0.1 mg |
| GeneralRef: | Ruano G, Windemuth A, Kocherla M, Holford T, Fernandez ML, Forsythe CE, Wood RJ, Kraemer WJ, Volek JS. Physiogenomic analysis of weight loss induced by dietary carbohydrate restriction. Nutr Metab (Lond). 2006 May 15;3:20. PMID: 16700901 |
| NotesMain: | This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. |
| Gene_Id: | 8513 |
| Omim_ID: | H00009388-M01 |
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