| CatalogCode: | NB100-40829 |
| ProductName: | SPTBN1 Antibody |
| Product Description: | Rabbit Polyclonal anti-SPTBN1 |
| Clonality: | Polyclonal |
| Immunogen: | This antibody maps to a region between residue 2150 and 2200 of human Spectrin Non-Erythroid Beta 1 using the numbering given in entry NP_003119.2 (GeneID 6711). |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 ml of antigen affinity purified rabbit antisera |
| Uses: | Western Blot and Immunoprecipitation. |
| Background: | SPTBN1 is a major constituent of the erythrocyte skeleton, accounting for 25% of the total membrane protein and 75% of the cytoskeletal mass. It is associated with the cytoplasmic surface of the membrane by attachment to ankyrin, a peripheral membrane protein. The membrane skeleton influences several cellular properties such as cell shape, restriction of mobility of the integral membrane protein exposed at the cell surface, and transmembrane movement of phospholipids and cholesterol. While the simplest form of SPTBN1 in solution is an alpha-beta heterodimer, SPTBN1 can undergo self-association in various conditions to form a tetramer of alpha2-beta2. In recent years a large number of SPTBN1-like molecules have been found in non-erythroid cells. These proteins are known by such different names as fodrin, CBP I, calspectin and TW 260/240. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| ListPrice: | 325 |
| AppSummary: | IP, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-SPTBN1 antibody, anti-Spectrin antibody, anti-Beta antibody, anti-Non-Erythroid 1 antibody, anti-SPTB2 antibody, anti-Spectrin Beta-2 antibody, anti-ELF antibody, anti-Embryonic Liver Beta-Fodrin antibody |
| ProteinTarget: | SPTBN1 |
| PackageSize: | 0.02 mg |
| Gene_Id: | 6711 |
| Omim_ID: | NB100-40828 |
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