| CatalogCode: | NB100-40811 |
| ProductName: | MSN Antibody |
| Product Description: | Goat Polyclonal anti-MSN |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide, C-NARDESKKTAND, representing the internal region of the human protein according to NP_002435.1 |
| CrossReactivity: | Human. Other species not tested. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 70kDa band observed in Human Spleen lysates (calculated MW of 67.8kDa according to NP_002435.1). Recommended concentration: 1-3µg/ml. |
| Background: | Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline [ pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-MSN antibody, anti-moesin antibody |
| ProteinTarget: | MSN |
| PackageSize: | 0.1 mg |
| Homology: | Mouse, Rat, Dog |
| GeneralRef: | Ivetic A, Florey O, Deka J, Haskard DO, Ager A, Ridley AJ. , Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering. ,J Biol Chem. 2004 Aug 6;279(32):33263-72. Epub 2004 Jun 3. , PMID: 15178693 |
| NotesMain: | Gene ID = 4478 (human); 17698 (mouse); 81521 (rat); |
| Gene_Id: | 4478 |
| Omim_ID: | H00004478-A01 |
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