| CatalogCode: | NB100-397 |
| ProductName: | MDC1 Antibody |
| Product Description: | Rabbit Polyclonal anti-MDC1 |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide, which represented a portion of human Mediator of DNA Damage Checkpoint Protein 1 encoded within exon 10 (LocusLink ID 9656). |
| Specificity: | This antibody is specific for MDC1. |
| CrossReactivity: | NB 100-397 recognizes human MDC1. Other species have not been tested. |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Uses: | This antibody may be used for Western Blot, where a doublet band should be seen at ~250 kDa.Suggested working dilutions: *Western Blot - 1:5,000-1:25,000Immunoprecipitation - 2-4 ug/mg lysateImmunofluorescence - ND*The investigator should determine the optimal working dilution for a specific application. |
| Background: | MDC1 (mediator of DNA damage checkpoint protein 1), which works with H2AX to promote recruitment of repair proteins to the sites of DNA breaks and controls damage-induced cell-cycle arrest checkpoints. Cells that lack MDC1 are sensitive to ionizing radiation. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate. pH 7-8 |
| ListPrice: | 285 |
| AppSummary: | IP, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-MDC1 antibody, anti-NFBD1 antibody, anti-NFBD-1 antibody, anti-Mediator of DNA Damage Checkpoint Protein 1 antibody, anti-nuclear factor with BRCT domains protein 1 antibody, anti-KIAA antibody |
| ProteinTarget: | MDC1 |
| PackageSize: | 0.1 ml |
| NotesMain: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |