| CatalogCode: | | NB100-369 |
| ProductName: | | RENT1 (aka: hUpf1) Antibody |
| Product Description: | | Goat Polyclonal anti-RENT1 (aka: hUpf1) |
| Clonality: | | Polyclonal |
| Immunogen: | | A synthetic peptide, representing a portion of human RENT1 encoded within exons 19 and 20 (LocusLink ID 5976). |
| Specificity: | | This antibody is specific for RENT1. |
| CrossReactivity: | | NB 100-369 recognizes human RENT1. Other species have not been tested. Reactivity with mouse and zebrafish is likely owing to conservation (27/28 and 28/28 residues, respectively) of the peptide used for this antibody production with the RENT1 orthologs of those species. |
| Packaging: | | 0.1 ml IgG purified Goat antisera. |
| Uses: | | By Western blot, this antibody recognizes a band at ~145 kDa, representing human RENT1. Suggested working dilutions: * Western Blot - 1:1,000-1:2,500 (ECL) Immunoprecipitation - ND Immunohistochemistry - ND *The investigator should determine the optimal working dilution for a specific application. |
| Control: | | 30 ug of lymphoblastoid whole cell extracts |
| Background: | | RENT1 (regulator of nonsense transcripts 1) is a group 1 RNA helicase, RNA-binding protein whose RNA-binding activity is modulated by ATP. It enters the nucleus where it influences early events in mRNA biogenesis. It functions in NMD (non-sense-mediated mRNA decay) in mammalian cells, ridding cells of aberrant mRNAs containing premature termination codons. |
| Storage: | | Store at 4C. Do not freeze. |
| Purity: | | IgG purified |
| Host_Name: | | Goat |
| Buffer: | | Tris-citrate/phosphate. pH 7-8 |
| ListPrice: | | 285 |
| AppSummary: | | WB |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-delta helicase antibody, anti-HUPF1 antibody, anti-KIAA0221 antibody, anti-nonsense mRNA reducing factor 1 antibody, anti-NORF1 antibody, anti-pNORF1 antibody, anti-regulator of nonsense transcripts 1 antibody, anti-up-frameshift mutation 1 homolog (S. cerevisiae) antibody, anti-UPF1 antibody, anti-yeast Upf1p homolog antibody |
| ProteinTarget: | | RENT1 (aka: hUpf1) |
| PackageSize: | | 0.1 ml |
| NotesMain: | | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |
| more information: | | company product webpage |