| CatalogCode: | NB100-364 |
| ProductName: | CSN2 Antibody |
| Product Description: | Rabbit Polyclonal anti-CSN2 |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide, representing a portion of human COP9 signalosome complex subunit 2 encoded within exons 8 and 9 (LocusLink ID 9318). |
| Specificity: | This antibody is specific for CSN2. |
| CrossReactivity: | NB 100-364 recognizes human CSN2. Other species have not been tested. Reactivity with mouse and D. melanogaster CSN2 expected due to sequence homology for immunizing peptide. |
| Packaging: | 0.1 ml of rabbit antisera (1 mg/ml) with Sodium Azide. |
| Uses: | By Western blot, this antibody recognizes a band at ~50 kDa, representing CSN2 protein. Suggested working dilutions: * Western Blot - 1:1,000-1:10,000 Immunoprecipitation - ND Immunohistochemistry - ND *The investigator should determine the optimal working dilution for a specific application. |
| Background: | COP9 signalosome is a conserved protein composed of eight subunits. Individual subunits of the complex have been linked to various signal transduction pathways leading to gene expression and cell cycle control. CSN2 is a transcriptional corepressor that encodes the second subunit of COP9 signalosome. CSN2 interacts with and regulates a subset of nuclear hormone receptors and is considered a novel repressor. It also plays a critical role in neuronal differentiation. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | IgG purified |
| Host_Name: | Rabbit |
| ListPrice: | 285 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-CSN2 antibody, anti-COP9 signalosome complex subunit 2 antibody, anti-COPS2 antibody, anti-COP9 constitutive photomorphogenic homolog subunit 2 antibody, anti-TRIP15 thyroid hormone receptor interactor 15 antibody, anti-ALIEN antibody, anti-homolog of drosophila ALIEN antibody, anti-Sgn2 antibody |
| ProteinTarget: | CSN2 |
| PackageSize: | 0.1 ml |
| NotesMain: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |