| Catalog Code: | NB100-337 |
| Product Type: | Primary Antibody |
| Product Name: | Ku80 Antibody |
| List Price: | 285 |
| Clonality: | Monoclonal |
| Gene ID: | 7520 |
| Host: | Mouse |
| Clone: | 9403 |
| Isotype: | IgG |
| Product Description: | Mouse Monoclonal anti-Ku80 (9403) |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | Originally identified as an autoantigen, the Ku protein are nuclear proteins found in eukaryotes. They exist as a heterodimer consisiting of Ku 70 and Ku 80, migrating at approximately 70 and 80 kDa respectively. They bind to DNA ends at double strand bre |
| Alternate Names: | anti-ATP dependent DNA helicase II 80 kDa subunit antibody, anti-ATP dependent DNA helicase II 86 Kd subunit antibody, anti-CTC box binding factor 85 kDa antibody, anti-CTC85 antibody, anti-CTCBF antibody, anti-DNA repair protein XRCC5 antibody, anti-KARP |
| Immunogen: | Recombinant protein encoding an N terminal fragment of human Ku 80 expressed in E. coli. |
| Localization: | Nuclear |
| Specificity: | This antibody is specific for Ku80. |
| Purity: | Protein G purified |
| Buffer: | Phosphate buffered saline |
| Packaging: | 0.1 ml of Protein G affinity purified ascitic fluid in PBS, pH 7.4. No preservatives. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | Western blot: use at a dilution of 1 / 2000.Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user.By Western blot, this antibody detects a band of 80 kDa, which corresponds to the predicted molecular wei |
| Application Summary: | WB |
| General References: | General / background references:Jackson SP The recognition of DNA damage. Curr Opin Genet Dev 6:19-25 (1996). Weaver DT What to do at an end: DNA double-strand-break repair. Trends Genet 11:388-92 (1995). |
| Notes Main: | Hybridoma: Fusion between BALB/c splenocytes and mouse myeloma cells (NS-1). |