| CatalogCode: | NB100-311 |
| ProductName: | Chk1 Antibody |
| Product Description: | Goat Polyclonal anti-Chk1 |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide, which represented a portion of human Cell Cycle Checkpoint Kinase encoded within exons 9 and 10 (LocusLink ID 1111). |
| Specificity: | NB 100-311 is specific for human Chk1 protein. |
| CrossReactivity: | NB 100-311 reacts with human. Other species have not been tested. Mouse and rat share 33/39 residues with the peptide used as the immunogen for this antibody. |
| Packaging: | 0.1 ml Goat antisera. |
| Uses: | 100-311 may be used for Western Blot where a band at ~53 kD is seen on SDS-PAGE. It may also be used for immunoprecipitation (band ~ 48 kDa). Suggested working dilutions: * Western Blot 1:1,000-1:10,000 (ECL) Immunocytochemistry Not Done Immunoprecipitation 5-20 ug/g lysate *The investigator should determine the optimal working dilution for a specific application. |
| Background: | In response to DNA damage and replication blocks, cells prevent cell cycle progression through the control of critical cell cycle regulators. Chk1 is an essential kinase for embryonic development and regulating mitotic progression in response to DNA damage. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Host_Name: | Goat |
| ListPrice: | 285 |
| AppSummary: | IP, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Cell cycle checkpoint kinase antibody, anti-CHEK1 antibody, anti-Serine/threonine protein kinase Chk1 antibody |
| ProteinTarget: | Chk1 |
| PackageSize: | 0.1 ml |
| NotesMain: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |
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