| Catalog Code: | NB100-309 |
| Product Type: | Primary Antibody |
| Product Name: | ATM Antibody |
| List Price: | 285 |
| Clonality: | Monoclonal |
| Gene ID: | 472 |
| Host: | Mouse |
| Clone: | 2C1 |
| Isotype: | IgG1 kappa |
| Product Description: | Mouse Monoclonal anti-ATM (2C1) |
| Cross Reactivity: | NB 100-309 reacts with human, monkey, rat, and mouse protein. |
| Species Summary: | Hu, Mu, Mk, Rt |
| Background: | Ataxia-telangiectasia (A-T) is a recessive childhood disease caused by mutations in the ATM (AT-mutated) gene. Symptoms include neurological abnormalities that cause unsteady posture, dilated blood vessels, infertility, radiation sensitivity, immune defi |
| Alternate Names: | anti-AT complementation group A antibody, anti-AT complementation group C antibody, anti-AT complementation group D antibody, anti-AT complementation group E antibody, anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxia tel |
| Immunogen: | Fusion protein expressed in E.coli corresponding to amino acids 2577-3056. |
| Specificity: | NB 100-309 recognizes full-length ATM, a 370-kDa nuclear phosphoprotein. |
| Purity: | protein G purified |
| Buffer: | PBS [pH7.2] |
| Packaging: | 0.1 ml protein G purified Mouse ascites. |
| Package Size: | 0.1 ml |
| Uses: | Uses: Western blotting, immunofluorescnece, immunoprecipitation, immunohistochemsitry. |
| Application Summary: | IHC, IF, IP, WB |
| General References: | 1. Suszuki, K. et al. Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation. JBC 274:25571-25575 (1999). 2. Chen, G. et al. The product of the ATM gene is a 370-kDa nuclear phosphoprotein. JBC 271:33693-33697 (1996). 3. Kozl |
| Notes Main: | Hybridoma: Fusion between BALB/c splenocytes and mouse myeloma (NS-1 cells). |
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