| CatalogCode: | | NB100-2918 |
| ProductName: | | ACSL5 Antibody |
| Product Description: | | Goat Polyclonal anti-ACSL5 |
| Clonality: | | Polyclonal |
| Immunogen: | | C-RTQIDSLYEHIQDC TerminusNP_057318.2; NP_976313.1; NP_976314.1 |
| CrossReactivity: | | Human. Other species not tested. |
| Packaging: | | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | | Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 75kDa band observed in Human Spleen lysates (calculated MW of 76.0kDa according to NP_976313.1and NP_976314.1). Recommended concentration: 1-3µg/ml. |
| Control: | | Human Spleen lysate |
| Background: | | The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. |
| Storage: | | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | | Immunogen affinity purified |
| Host_Name: | | Goat |
| Buffer: | | Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| ListPrice: | | 295 |
| AppSummary: | | ELISA, WB |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-ACSL5 antibody, anti-acyl-CoA synthetase long-chain family member 5 antibody, anti-HGNC:16526 antibody, anti-ACS2 antibody, anti-ACS5 antibody, anti-FACL5 antibody, anti-fatty-acid-Coenzyme A ligase antibody, anti-long-chain 5 antibody, anti-long-chain acyl-CoA synthetase 5 antibody, anti-long-chain fatty ac antibody |
| ProteinTarget: | | ACSL5 |
| PackageSize: | | 0.1 mg |
| Homology: | | Human |
| GeneralRef: | | Obermuller N, Keith M, Kopitz J, Autschbach F, Schirmacher P, Gassler N. Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5.Int J Colorectal Dis. 2005 Apr 5; [Epub ahead of print] PMID: 15809837 |
| NotesMain: | | This antibody is expected to recognise isoform a (NP_057318.2) and isoform b (NP_976313.1 and NP_976314.1). |
| Gene_Id: | | 51703 |
| Omim_ID: | | H00006296-B01 |
| more information: | | company product webpage |