| CatalogCode: | NB100-2892 |
| ProductName: | hnRNP-H Antibody |
| Product Description: | Rabbit Polyclonal anti-hnRNP-H |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized maps to a region between residue 400 and the C-terminus(residue 448) of human Heterogeneous Nuclear Ribonucleoprotein H1 using the numbering given in entry NP_005511.1 (GeneID 3187). |
| Specificity: | This antibody is specific for immunohistochemistry. |
| CrossReactivity: | Human and mouse. Other species have not been tested. |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry. No other applications have been tested. Suggested working dilution: *Formalin-Fixed Paraffin-Embedded Tissue 1:100 - 1:500Epitope exposure is recommended.Epitope exposure with citrate buffer will enhance staining.Likely to work with frozen sections*The investigator should determine the optimal working dilution for a specific application. |
| Background: | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| ListPrice: | 350 |
| AppSummary: | IHC |
| SpeciesSummary: | Hu, Mu |
| ALTnames: | anti-HNRNPH1 antibody, anti-hnRNPH1 antibody, anti-heterogeneous nuclear ribonucleoprotein H antibody |
| ProteinTarget: | hnRNP-H |
| PackageSize: | 0.1 ml |
| Gene_Id: | 3187 |
| Omim_ID: | NB100-78552 |