| CatalogCode: | NB100-2887 |
| ProductName: | MSH2 Antibody |
| Product Description: | Rabbit Polyclonal anti-MSH2 |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized maps to a region between residue 875 and the C-terminus(residue 934) of human mutS homolog 2 using the numbering given in Swiss-Prot entry P43246(GeneID 4436). |
| Specificity: | This antibody is specific for immunohistochemistry. |
| CrossReactivity: | Human and mouse. Other species have not been tested. |
| Packaging: | 0.1 ml of affinity purified rabbit antisera. |
| Uses: | This antibody is useful for immunohistochemistry. No other applications have been tested. Suggested working dilution: *Formalin-Fixed Paraffin-Embedded Tissue 1:100 - 1:500Epitope exposure is recommended.Epitope exposure with citrate buffer will enhance staining.Likely to work with frozen sections*The investigator should determine the optimal working dilution for a specific application. |
| Background: | MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| ListPrice: | 350 |
| AppSummary: | IHC |
| SpeciesSummary: | Hu, Mu |
| ALTnames: | anti-MSH2 antibody, anti-MSH-2 antibody, anti-mutS homolog 2 antibody, anti-COCA1 antibody, anti-Colon Cancer 1 antibody, anti-FCC1 antibody, anti-Cancer 1 antibody, anti-HNPCC1 antibody, anti-HNPCC antibody, anti-Hereditary Nonpolyposis Colon Cancer 1 antibody |
| ProteinTarget: | MSH2 |
| PackageSize: | 0.1 ml |
| Gene_Id: | 4436 |
| Omim_ID: | NB100-198 |
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