| Catalog Code: | NB100-2831 |
| Product Type: | Primary Antibody |
| Product Name: | BARK1 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 156 |
| Host: | Goat |
| Product Description: | Goat Polyclonal anti-BARK1 |
| Cross Reactivity: | Human. Other species not tested. Reactivity based upon sequence homology: Mouse, Rat, Dog |
| Species Summary: | Hu |
| Background: | Beta-adrenergic receptor kinase (ADRBK1) phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. ADRBK1 is an ubiquitous cytosolic enzyme that specifically phosphorylat |
| Alternate Names: | anti-ADRBK1 antibody, anti-adrenergic antibody, anti-beta antibody, anti-receptor kinase 1antibody, anti-BARK1 antibody, anti-BETA-ARK1 antibody, anti-GRK2 antibody, anti-beta adrenergic receptor kinase 1 antibody |
| Immunogen: | Synthetic peptide: C-RDAYREAQQLVQR, representing the internal region of the human protein according to NP_001610.1 |
| Purity: | Immunogen affinity purified |
| Buffer: | Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx 75-80kDa band observed in Human lysates of Burkitt's lymphoma cell line Daudi (calculated MW of 79.7kDa according to NP_001610.1). Recommended concentration: 0.3-1.0ug/ml. |
| General References: | Iaccarino G, Barbato E, Cipolletta E, De Amicis V, Margulies KB, Leosco D, Trimarco B, Koch WJ. Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure. Eur Heart J. 2005 Sep;26(17):1752-8. Epub 2005 Jul 29. PMID: 16055494 |