| Catalog Code: | NB100-270 |
| Product Type: | Primary Antibody |
| Product Name: | ATM Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 472 |
| Host: | Goat |
| Product Description: | Goat Polyclonal anti-ATM |
| Cross Reactivity: | NB 100-270 recognizes human and mouse ATM. Other species have not been tested. |
| Species Summary: | Hu, Mu |
| Background: | Ataxia-telangiectasia (A-T) is a recessive childhood disease caused by mutations in the ATM (AT-mutated) gene. Symptoms include neurological abnormalities that cause unsteady posture, dilated blood vessels, infertility, radiation sensitivity, immune defi |
| Alternate Names: | anti-AT complementation group A antibody, anti-AT complementation group C antibody, anti-AT complementation group D antibody, anti-AT complementation group E antibody, anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxia tel |
| Immunogen: | A synthetic peptide (within amino acids 1653-2032), which represented a portion of human Ataxia Telangiectasia Mutated, specifically encoded in part by exons 36 and 37 (LocusLink ID 472). |
| Localization: | Nuclear. Found also in endocytic vesicles in association with beta adaptin. |
| Specificity: | This antibody is specific for human ATM. |
| Purity: | Affinity purified |
| Buffer: | Tris-citrate/phosphate, pH 7-8 |
| Packaging: | 0.1 mg Affinity purified Goat antisera. |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | Western blot and immunoprecipitation. |
| Application Summary: | IP, WB |
| Novus References: | 1. Dirlam, A. et al. Deregulated E2f-2 underlies cell cycle and maturation defects in Rb null erythroblasts. Mol. Cell. Biol. 10.1128/MCB.01118-07, Oct 2007 |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |