| CatalogCode: | NB100-2677 |
| ProductName: | Integrin alpha V beta 3 Antibody |
| Product Description: | Mouse Monoclonal anti-Integrin alpha V beta 3 (23C6) |
| Clone: | 23C6 |
| Clonality: | Monoclonal |
| Immunogen: | Cell preparation: A cell suspension containing osteoclasts from osteoclastomas. |
| Specificity: | Reacts with alpha V beta 3. 23C6 may be useful for bone resorption modulation, osteoclast identification, receptor purification, malignant melanoma identification and treatment. |
| CrossReactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.25 mg |
| Uses: | FACS: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Note: samples should be acetone fixed.IP: Use at an assay dependent dilution. Neut: Use at an assay dependent dilution. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cell Membrane |
| Control: | Positive control: Tonsil. 125/124 kDa (reduced), 150kDa (non-reduced). |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | Preservative: NoneConstituents: PBS |
| ListPrice: | 295 |
| AppSummary: | FACS, IHC-Fr, IP |
| ProteinTarget: | Integrin alpha V beta 3 |
| PackageSize: | 0.25 mg |
| GeneralRef: | This product has been used in:Marshall JF et al. Alpha v beta 1 is a receptor for vitronectin and fibrinogen, and acts with alpha 5 beta 1 to mediate spreading on fibronectin. J Cell Sci 108 ( Pt 3):1227-38 (1995). Horton MA et al. Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens. Cancer Res 45:5663-9 (1985). |
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