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| Catalog Code: | NB100-2652 |
| Product Name: | Fibronectin Antibody |
| Product Description: | Mouse Monoclonal anti-Fibronectin (Fn-3) |
| Clone: | Fn-3 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Human fibronectin expressed by simian virus 40 transformed human mammary epithelial cells. |
| Specificity: | Reacts with human cellular fibronectin, but not plasma fibronectin. |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.1 mg IgG purified Mouse ascites. |
| Uses: | IHC-P: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic and secreted protein (extracellular space; extracellular matrix). |
| Background: | Fibronectin is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. They occur as dimers of two 200 kDa subunits. They have binding domains for bacterial proteins, collagens, heparin-like molecules and fibrin. Cellular fibronectin is widely distributed in the stroma of malignant tumours. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | PBS |
| Application Summary: | Immunohistochemistry-Paraffin, immunoprecipitation, |
| Species Summary: | Hu |
| Alternate Names: | anti-CIG antibody, anti-Cold insoluble globulin antibody, anti-DKFZp686F10164 antibody, anti-DKFZp686H0342 antibody, anti-DKFZp686I1370 antibody, anti-DKFZp686O13149 antibody, anti-fibronectin 1 antibody, anti-FINC antibody, anti-FN 1 antibody, anti-FN antibody, anti-FN1 antibody, anti-LETS antibody, anti-MSF antibody, anti-Transformation sensitive protein. antibody |
| Package Size: | 0.1 mg |
| Preservative: | None |
| General References: | This product has been used in:Keen J et al. Monoclonal antibodies that distinguish between human cellular and plasma fibronectin. Mol Biol Med 2:15-27 (1984). |
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more information: | company product webpage |