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| Catalog Code: | NB100-2563 |
| Product Name: | ALDH1A1 Antibody |
| Product Description: | Goat Polyclonal anti-ALDH1A1 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 216 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide: C-RELGEYGFHEYTE, representing the internal region of the human protein according to NP_000680.2 |
| Cross Reactivity: | Human. Other Species have not been tested. Expected cross-reactivity based upon sequence homology: Human, Mouse, Rat |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 55kDa band observed in Human Liver lysates (calculated MW of 54.9kDa according to NP_000680.2). Recommended concentration: 1-3µg/ml. |
| Background: | This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Goat |
| Buffer: | Tris-saline , [pH7.3] with 0.5% BSA |
| Application Summary: | ELISA pep 1:32,000, Western Blot 1 to 3 ug/ml |
| Species Summary: | Hu |
| Alternate Names: | anti-ALDH1A1 antibody, anti-aldehyde dehydrogenase 1 family antibody, anti-member A1antibody, anti-ALDC antibody, anti-ALDH-E1 antibody, anti-ALDH1 antibody, anti-ALDH11 antibody, anti-MGC2318 antibody, anti-PUMB1 antibody, anti-RALDH1 antibody, anti-ALDH class 1 antibody, anti-acetaldehyde dehydrogenase 1 antibody, anti-aldehyde dehydrogenase 1 antibody, anti-soluble antibody, anti-aldehyde dehydrogenase 1A1 antibody, anti-aldehyde dehydrogenase antibody, anti-liver cytosolic antibody, anti-retinal dehydrogenase 1 antibody |
| Package Size: | 0.1 mg |
| Preservative: | .02% Sodium azide |
| General References: | Everts HB, King LE Jr, Sundberg JP, Ong DE. . Hair cycle-specific immunolocalization of retinoic acid synthesizing enzymes Aldh1a2 and Aldh1a3 indicate complex regulation.. J Invest Dermatol. 2004 Aug;123(2):258-63. . PMID: 15245423 |
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