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| Catalog Code: | NB100-247 |
| Product Name: | Claspin Antibody |
| Product Description: | Rabbit Polyclonal anti-Claspin |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Gene ID: | 63967 |
| Concentration: | 1 mg/ml |
| Immunogen: | The epitope recognized by this antibody maps to a region between residues 450 and 500 of human Claspin using the numbering given in entry AAG24515.1 (GeneID 63967). |
| Cross Reactivity: | Human. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | This antibody is useful for Western blot and immunoprecipitation. By Western blot a band at approximately 180 kDa is seen. |
| Localization: | Nucleus. |
| Background: | Claspin is a cell cycle regulated protein. It plays a critical role in replication checkpoint control and interacts with the checkpoint proteins ATR and Rad9. It also associates with Chk1, but only following replication stress or other types of DNA damage. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Host Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 |
| Application Summary: | immunoprecipitation - 1 to 5 ug/ml of lysate, Western Blot - 1:5,000-1:20,000 |
| Species Summary: | Hu |
| Alternate Names: | anti-Clspn antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.09% Sodium Azide |
| Notes Main: | Blocking peptide is available or can be made for this item. Lead time is 3 days to 4 weeks. Price is $ 150/0.25 ml (or 50 ug). Please enquire availability. |
| Novus References: | 1. Ge Li, R.T., et al. Phosphatase type 2A-dependent and -independent pathways for ATR phosphorylation of Chk1. J. Biol. Chem. 282(10): 7287-7298 (2007). |
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