| CatalogCode: | NB100-2422 |
| ProductName: | PCK2 Antibody |
| Product Description: | Goat Polyclonal anti-PCK2 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: KPWKPGDKEPCAH, representing the internal region of the human protein according to NP_004554.2 |
| Specificity: | This antibody is expected to recognise isoform 1 (NP_004554) only, no cross-reactivity with PCK1. |
| CrossReactivity: | Human. Other species have not been tested. Expected reactivity based upon sequence homology: Human |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:8,000.
Western Blot: Approx 75kDa band observed in Human Liver lysates (calculated MW of 70.7kDa according to NP_004554.2). Recommended concentration: 0.5-1.0 ug/ml. |
| Background: | Gene ID(s): 5106 (human) |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-PCK2 antibody, anti-phosphoenolpyruvate carboxykinase 2 (mitochondrial) antibody, anti-HGNC:8725 antibody, anti-PEPCK antibody, anti-PEPCK-M antibody, anti-PEPCK2antibody, anti-PEP carboxykinase antibody, anti-mitochondrial phosphoenolpyruvate carboxykinase 2 antibody, anti-phosphoenolpyruvate carboxylase antibody, anti-phosphopyruvate carboxylase antibody |
| ProteinTarget: | PCK2 / PEPCK-M |
| PackageSize: | 0.1 mg |
| GeneralRef: | Duplus E, Benelli C, Reis AF, Fouque F, Velho G, Forest C. Expression of phosphoenolpyruvate carboxykinase gene in human adipose tissue: induction by rosiglitazone and genetic analyses of the adipocyte-specific region of the promoter in type 2 diabetes. Biochimie. 2003 Dec;85(12):1257-64. PMID: 14739078
|
| NotesMain: | This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described. |
| Gene_Id: | 5106 |
| Omim_ID: | H00054825-A01 |
order or
more information: | company product webpage |
| request information: |
|