| CatalogCode: | NB100-2409 |
| ProductName: | SLITRK1 Antibody |
| Product Description: | Goat Polyclonal anti-SLITRK1 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: NADGAHRVYDCGSHS, representing the C Terminus of the human protein according to NP_443142 |
| CrossReactivity: | Expected reactivity based upon sequence homology: Human, Mouse, Rat, Dog |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | Peptide ELISA: antibody detection limit dilution 1:64,000.
Western Blot: Preliminary experiments in Human Brain lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? |
| Background: | Gene ID(s): 114798 (human) |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| ListPrice: | 195 |
| AppSummary: | ELISA, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-SLITRK1 antibody, anti-SLIT and NTRK-like family antibody, anti-member 1 antibody, anti-HGNC:20297 antibody, anti-KIAA0918 antibody, anti-KIAA1910 antibody, anti-LRRC12 antibody, anti-RP11-395N17.1antibody, anti-leucine rich repeat containing 12 antibody, anti-slit and trk like 1 protein antibody, anti-slit and trk like gene 1 antibody |
| ProteinTarget: | SLITRK1 |
| PackageSize: | 0.1 mg |
| GeneralRef: | Abelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, Morgan TM, Mathews CA, Pauls DL, Rasin MR, Gunel M, Davis NR, Ercan-Sencicek AG, Guez DH, Spertus JA, Leckman JF, Dure LS 4th, Kurlan R, Singer HS, Gilbert DL, Farhi A, Louvi A, Lifton RP, Sestan N, State MW. Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science. 2005 Oct 14;310(5746):317-20. PMID: 16224024
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| NotesMain: | **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application Members of the SLITRK family, such as SLITRK1, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, but not SLITRK1, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003).[supplied by OMIM] |
| Gene_Id: | 114798 |
| Omim_ID: | NB100-79812 |
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