| Catalog Code: | NB100-2388 |
| Product Type: | Primary Antibody |
| Product Name: | ZMPSTE24 Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 10269 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-ZMPSTE24 |
| Cross Reactivity: | Human. Other species not tested. |
| Species Summary: | Hu |
| Background: | ZMPSTE24 is a zinc metalloprotease involved in the post-translational processing of LMNA precursors. Mutations in ZMPSTE24 have been associated with human diseases, often due to the accumulation of LMNA precursors. It is possible that ZMPSTE24, due to its |
| Alternate Names: | anti-ZMPSTE24 antibody, anti-zinc metallopeptidase (STE24 homolog antibody, anti-yeast) antibody, anti-FACE-1 antibody, anti-FACE1 antibody, anti-FLJ14968 antibody, anti-MADB antibody, anti-STE24 antibody, anti-Ste24p antibody, anti-CAAX prenyl protease a |
| Immunogen: | A synthetic peptide made to a C-terminal portion of the human ZMPSTE24 protein sequence (between residues 400-475). [Swiss-Prot O75844] |
| Localization: | Integral membrane, primarily ER |
| Specificity: | This antibody is specific for ZMPSTE24. |
| Purity: | peptide affinity purified |
| Buffer: | Tris-glycine, 150mM NaCl |
| Packaging: | 0.1 ml peptide affinity purified Rabbit antisera. |
| Package Size: | 0.1 ml |
| Concentration: | 0.95 mg/ml |
| Uses: | By Western blot a band is seen at ~54 kDa, representing ZMPSTE24 protein. |
| Application Summary: | WB, ECL |
| General References: | 1. Corrigan, DP, et al. Biochem. J. 387: 129-138 (2005)2. Young, SG, et al. Lipid Res. 46: 2531-2558 (2005) |