| Catalog Code: | NB100-2384 |
| Product Type: | Primary Antibody |
| Product Name: | PDK1 Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 5163 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-PDK1 |
| Cross Reactivity: | This antibody reacts with human. No other species have been tested. The immunogen used for this antibody production has 100% homology with mouse, rat, and monkey PDK1 protein. |
| Species Summary: | Hu |
| Background: | Pyruvate dehydrogenase kinase isoform 1 (PDK1) inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism. |
| Alternate Names: | anti-PDK1 antibody, anti-pyruvate dehydrogenase kinase antibody, anti-isoenzyme 1antibody, anti-HGNC:8809 antibody, anti-mitochondrial pyruvate dehydrogenase kinase isoenzyme 1 antibody, anti-pyruvate dehydrogenase kinase antibody, anti-isoenzyme 1 antibo |
| Immunogen: | A synthetic peptide made to an internal portion of the human PDK1 protein sequence (between residues 300-400). [Swiss-Prot Q15118] |
| Localization: | Mitochondrion |
| Specificity: | This antibody is specific for PDK1. |
| Purity: | Affinity purified |
| Buffer: | Tris-glycine, 150mM NaCl |
| Packaging: | 0.1 ml of affinity purified rabbit antisera. |
| Package Size: | 0.1 ml |
| Concentration: | 0.5 mg/ml |
| Uses: | By Western blot a band is seen at ~49 kDa, representing PDK1 protein. There are also two higher and one lower non-specific molecular weight bands. No other applications have been tested. Recommended Starting Dilutions:* Western Blot: 0.5-2.0 ug/ml (ECL) |
| Application Summary: | WB |