| CatalogCode: | NB100-2316 |
| ProductName: | PKD3 Antibody |
| Product Description: | Rabbit Polyclonal anti-PKD3 |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized by NB 100-2316 maps to a region between residue 840 and the C-terminus (residue 890) of human Protein Kinase D3 using the numbering given in Swiss-Prot entry O9806 (GeneID 23683). |
| CrossReactivity: | Human. Other species have not been tested. Reactivity with mouse is expected owing to complete identity between this ortholog and human PKD3 at the site to which the epitope maps. |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested starting dilutions are as follows.Western Blot: 1:1,000 |
| Background: | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate, pH 7 to 8 |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-PKD3 antibody, anti-PKD-3 antibody, anti-Protein Kinase D3 antibody, anti-PKC-NU antibody, anti-Protein Kinase C nu antibody, anti-EPK2 antibody |
| ProteinTarget: | PKD3 |
| PackageSize: | 0.1 ml |
| Gene_Id: | 23683 |
| Omim_ID: | NB600-1370 |
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