| CatalogCode: | NB100-2301 |
| ProductName: | TIAM1 Antibody |
| Product Description: | Rabbit Polyclonal anti-TIAM1 |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized by NB 100-2301 maps to a region between residues 1550 and the C-terminus (residue 1591) of human T-cell lymphoma invasion and metastasis 1 using the numbering given in entry NP_003244.1 (GeneID 7074) |
| CrossReactivity: | Human and mouse. Other species have not been tested. |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested starting dilutions are as follows.Western Blot: 1:1,000 |
| Background: | TIAM1 modulates the activity of RHO like proteins and connects extracellular signals to cytoskeletal activities. It acts as a GDP dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO like GTPases and activates them. It activates RAC1, CDC42, and to a lesser extent RHOA. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate, pH 7 to 8 |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu, Mu |
| ALTnames: | anti-TIAM1 antibody, anti-T-cell lymphoma invasion and metastasis 1 antibody |
| ProteinTarget: | TIAM1 |
| PackageSize: | 0.1 ml |
| Gene_Id: | 7074 |
| Omim_ID: | H00026230-A01 |
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