| CatalogCode: | NB100-2295 |
| ProductName: | LNK Antibody |
| Product Description: | Goat Polyclonal anti-LNK |
| Clonality: | Polyclonal |
| Immunogen: | Corresponding to amino acids NGPALQPSSPC, from the N Terminus of the LNK protein sequence according to NP_005466. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Goat antisera. |
| Uses: | This antibody can be used in Western Blot where a band at approximately 70kDa is detected.Recommended Starting Dilutions*:WB: 0.3-1.0ug/ml.ELISA: 1/64,000*Optimal dilutions should be determined by the end user.Not tested in any other applications. |
| Control: | Tcell line MOLT4 lysate |
| Background: | T-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM] |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Goat |
| Buffer: | Tris saline containing 0.02% Na azide [pH7.3] with 0.5% BSA |
| ListPrice: | 295 |
| AppSummary: | WB, ELISA |
| SpeciesSummary: | Hu |
| ALTnames: | anti-Ligand of Numb Protein X antibody, anti-MPDZ antibody, anti-Multiple PDZ Domain Containing Protein antibody |
| ProteinTarget: | LNK |
| PackageSize: | 0.1 mg |
| GeneralRef: | Li Y, He X, Schembri-King J, Jakes S, Hayashi J. Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation. J Immunol. 2000 May 15;164(10):5199-206. PMID: 10799879 |
| Gene_Id: | 10019 |
| Omim_ID: | NB100-66230 |