| Catalog Code: | NB100-2279 |
| Product Type: | Primary Antibody |
| Product Name: | 53BP1 Antibody |
| List Price: | 375 |
| Clonality: | Polyclonal |
| Gene ID: | 7158 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-53BP1 |
| Cross Reactivity: | Human and mouse. Other species have not been tested. |
| Species Summary: | Hu, Mu |
| Background: | P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also sug |
| Alternate Names: | anti-53BP1 antibody, anti-53BP-1 antibody, anti-TP53BP1 antibody, anti-Tumor Protein p53 Binding Protein 1 antibody |
| Immunogen: | Immunogen for NB 100-2279 was a phosphorylated synthetic peptide, which represented a portion of human p53 Binding Protein 1 (GeneID 7158) around serine 25 according to the numbering given in entry NP_005648.1. |
| Purity: | Affinity purified |
| Buffer: | Tris-buffered Saline containing 0.1% BSA |
| Packaging: | 0.1 ml of affinity purified rabbit antisera. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator.* Suggested starting dilutions are as follows: Formalin-Fixed Paraffin-Embedded Tissue 1:100 - 1:500 Epitope exposure is recommended. Epitope exposure with citrate buffer wi |
| Application Summary: | IHC |