| CatalogCode: | NB100-2232 |
| ProductName: | HDAC2 Antibody |
| Product Description: | Rabbit Polyclonal anti-HDAC2 |
| Clonality: | Polyclonal |
| Immunogen: | The epitope recognized by NB 100-2232 maps to the N-terminus of human Histone Deacetylase 2 using the numbering given in entry NP_001518.1 (GeneID 3066). |
| Specificity: | This antibody is specific to the human HDAC2 protein. |
| CrossReactivity: | Human. Other species have not been tested. |
| Packaging: | 0.1 ml Affinity purified Rabbit antisera. |
| Uses: | Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use.Suggested starting dilutions are as follows:*Western Blot: Not Recommended. Use rabbit anti-HDAC2 antibody NB 100-2233.Immunoprecipitation: 2 to 5 mcg/mg lysate*Investigator should determine optimal working conditions and dilutions. |
| Background: | Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 |
| ListPrice: | 295 |
| AppSummary: | IP, WB |
| SpeciesSummary: | Hu |
| ALTnames: | anti-HD2 antibody, anti-Histone deacetylase 2 (HD2) antibody, anti-histone deacetylase 2 antibody, anti-RPD3 antibody, anti-transcriptional regulator homolog RPD3 antibody |
| ProteinTarget: | HDAC2 |
| PackageSize: | 0.1 ml |
| Gene_Id: | 3066 |
| Omim_ID: | NB100-2282 |