| CatalogCode: | NB100-2215SS |
| ProductName: | SREBP1 Antibody |
| Product Description: | Rabbit Polyclonal anti-SREBP1 **Sample Size** |
| Clonality: | Polyclonal |
| Immunogen: | A synthetic peptide made to a portion of the human SREBP1 protein sequence (between residues 300-400). |
| Specificity: | This antibody is specific for SREBP1. |
| CrossReactivity: | This antibody reacts with mouse SREBP1 protein. Preliminary results with human protein (liver) were not positive. No other species have been tested. |
| Packaging: | 0.025 ml Affinity purified Rabbit antisera. |
| Uses: | By Western blot a band is seen at ~65 kDa. *Optimal working dilutions should be determined by the investigator. |
| Localization: | Integral membrane protein that moves from ER to Golgi in absence of sterols. |
| Control: | Mouse liver lysate |
| Background: | SREBP (Sterol Regulatory Element Binding Protein) 1 and 2 are transcription factors which participate in the control of cholesterol homeostasis. SREBP proteins, which are attached to the endoplasmic reticulum and nuclear envelope, are proteolytically cleaved and thus activated in response to conditions of low cellular sterol. SREBPs may also play some role in the apoptotic processes. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Affinity purified |
| Host_Name: | Rabbit |
| Buffer: | Tris-glycine and 150mM NaCl |
| ListPrice: | 100 |
| AppSummary: | WB |
| SpeciesSummary: | Mu |
| ALTnames: | anti-Sterol regulatory element binding protein 1 antibody, anti-SRBP1 antibody, anti-Sterol regulatory element-binding transcription factor antibody |
| PackageSize: | 0.025 ml |
| Homology: | 100% Mu, Rt, Po, Ha (Chinese) |
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