| CatalogCode: | | NB100-2198 |
| ProductName: | | CD102 Antibody |
| Product Description: | | Rat Monoclonal anti-CD102 (mlC2/4 (3C4)), conjugated to PE |
| Clone: | | mlC2/4 (3C4) |
| Clonality: | | Monoclonal |
| Immunogen: | | COS cells transfected with murine ICAM-2 |
| Specificity: | | This antiobdy recognizes murine intercellular adhesion molecule-2 (ICAM-2) aslo know as CD102. Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA-1(1). Serotec recommend the use of MCA2295EL for this purpose. |
| CrossReactivity: | | Cross-reacts with Mouse. Not tested in any other application. |
| Packaging: | | 0.1 mg Rat ascites. |
| Uses: | | FACS: Use 10ul of the suggested working dilution to label 106cells in 100ul. Not tested in any other applications. Optimal dilution should be determined by the end user. |
| Localization: | | Type I membrane protein |
| Background: | | Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1. Reports suggest that CD102 may play a role in lymphocyte re-circulation and T-cell activation. |
| Storage: | | Store at 4C. Do not freeze. |
| Isotype: | | IgG |
| Host_Name: | | Rat |
| Buffer: | | PBS pH7.4 and 1% BSA |
| ListPrice: | | 285 |
| AppSummary: | | FACS |
| SpeciesSummary: | | Mu |
| ALTnames: | | anti-ICAM-2 antibody |
| ProteinTarget: | | CD102/ICAM-2 |
| PackageSize: | | 0.1 mg |
| Conjugate: | | PE |
| GeneralRef: | | 1. Xu, H. et al. (1996) Characterization of murine intercellular adhesion molecule - 2. J. Immunol. 156:4909 - 4914. 2. Soede, R.D. et al. (1999) LFA-1 to LFA-1 signals involve zeta-associated protein-70 (ZAP-70) tyrosine kinase: Relevance for invasion and migration of a T-cell hybridoma. J. Immunol. 163:4253-4261. |
| NotesMain: | | Reconstitute with 1ml of distilled water. |
| more information: | | company product webpage |