| Catalog Code: | NB100-219 |
| Product Type: | Primary Antibody |
| Product Name: | ATM Antibody |
| List Price: | 285 |
| Clonality: | Monoclonal |
| Gene ID: | 472 |
| Host: | Mouse |
| Clone: | 3E8 |
| Isotype: | IgG1 kappa |
| Product Description: | Mouse Monoclonal anti-ATM (3E8) |
| Cross Reactivity: | This antibody reacts with human, monkey, rat, and mouse proteins. It has not been tested for reactivity with any other species. |
| Species Summary: | Hu, Mu, Mk, Rt |
| Background: | Ataxia-telangiectasia (A-T) is a recessive childhood disease caused by mutations in the ATM (AT-mutated) gene. Symptoms include neurological abnormalities that cause unsteady posture, dilated blood vessels, infertility, radiation sensitivity, immune defic |
| Alternate Names: | anti-AT complementation group A antibody, anti-AT complementation group C antibody, anti-AT complementation group D antibody, anti-AT complementation group E antibody, anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxia tel |
| Immunogen: | Recombinant protein expressed in E. coli corresponding to amino acids 980-1512. |
| Specificity: | NB 100-219 recognizes full-length ATM, a 370 kDa nuclear phosphoprotein. |
| Purity: | protein G purified |
| Buffer: | PBS [pH 7.4] |
| Packaging: | 0.1 ml protein G purified Mouse ascites. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | This product has been used in Western blot and immunoprecipitation. |
| Application Summary: | IP, WB |
| General References: | 1. Andegeko, Y, et al. (2001) Nuclear Retention of ATM at Sites of DNA Double strand breaks. JBC. 276: 38224-38230. 2. Suzuki, K., et al. (1999) Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation. JBC. 274: 25571-25575. 3. |
|